Journal of Food, Nutrition and Population Health Open Access

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Effects of hibiscus and lemon verbena polyphenols in overweight volunteers: the role of appetite related hormones

2nd EuroSciCon Conference on Food Technology
May 14-16, 2018 Rome, Italy

Marina Boix-Castejon, Maria Herranz-Lopez, Marilo OlivaresVicente, Enrique Barrajon-Catalan, Enrique Rocheand Vicente Micol

ISABIAL-FISABIO Foundation, Spain Miguel Hernandez University of Elche, Spain CIBERobn, Spain

Posters & Accepted Abstracts: J Food Nutr Popul Health

Abstract:

Introduction: Obesity has become a major global health problem with epidemic proportions. Calorie restriction, physical exercise or psychologic supports have failed to achieve efficient long-term weight loss maintenance or metabolic control. Plant-derived polyphenols have shown potential to alleviate obesity-related pathologies by a multi-targeted mechanism in animal models and human intervention studies. Materials & Methods: A dietary supplement based on a combination of Lippia citriodora (LC) and Hibiscus sabdariffa (HS) polyphenolic extracts was assayed in a double blind and placebo-controlled intervention study with 54 overweight volunteers having an isocaloric diet for two months. Results: The results showed an improvement of decreased hunger and appetite compared to the placebo group. These satiety changes in the intervention group correlated with a reduction in circulating resistin and normalization of leptin expression, while regulating ghrelin levels. A positive perception of the consumer´s health status was reflected using the SF-36 questionnaire. Contrary to the weight regain effect expected upon calorie restriction, we observed that plant polyphenols increased anorexigenic hormones (GLP-1) and decrease orexigenic hormones (ghrelin), leading to the compensation between hunger and energy expenditure and narrowing energy gap. Conclusions: Although further research may be required, we propose that the polyphenolic combination may be used for weight management by increasing long-term weight loss maintenance through the modulation of appetite biomarkers.

Biography :

Marina Boix Castejón is a PhD student at the Miguel Hernández University. She has graduated in Human Nutrition and Diabetics, has a Master's Degree in Clinical and Community Nutrition and Expert Course in Sports Nutrition from the University of Alicante, Spain.
Email:marinaboix@hotmail.com