Department of Gastroenterology and Hepatology, University in Wuhan, Wuchang, China
Research Article
CT-Based Radiomics Nomogram for Preoperative Evaluation of Overall Survival in Intrahepatic Cholangiocarcinoma after Surgical Resection
Author(s): Yuguo Wei*
Purpose: The purpose of this study was to establish a radiomics nomogram based on multi-phase
contrast-enhanced Computed Tomography (CT) for preoperative prediction of Overall Survival (OS) in
Intrahepatic Cholangiocarcinoma (ICC) after resection.
Methods: A cohort of 96 (7:3 in the training and validation cohorts) ICC patients was enrolled in this
study. All patients underwent a preoperative enhanced CT examination and then accepted the ICC
resection. Radiomics features were extracted from Arterial Phase (AP) and Portal Venous Phase (PVP)
contrast-enhanced CT images, respectively. The Least Absolute Shrinkage and Selection Operator
(LASSO) Cox regression was used to select the features. Radiomics and clinical features were
combined to build the nomogram to predict the OS. ICC patients were divided into high and low risk
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