Journal of Clinical Gastroenterology and Hepatology Open Access

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The Efficacy of Tocotrienols in the Treatment of Non-alcoholic Steatohepatitis: A Systematic Review

Annual Summit on Hepatology and Pancreatic Diseases
November 12-13, 2018 Paris, France

Higinio T. Mappala

Jose Reyes Mem. Medical Center, Philippines

Posters & Accepted Abstracts: J Clin Gastroenterol Hepatol

Abstract:

Non-alcoholic fatty liver disease (NAFLD) is one of the most common forms of chronic liver disease which may progress to nonalcoholic steatohepatitis (NASH). Currently there are no therapeutic strategies for such disease. Only lifestyle modification through diet and exercise were proven to afford some benefit in patients with NAFLD. No pharmacologic agents have so far been approved for the treatment of NAFLD or NASH. Therefore, most clinical efforts have been directed at treating the components of metabolic syndrome, namely obesity, diabetes, hypertension and dyslipidemias. Other interventions are directed at specific pathways potentially involved in the pathogenesis of NAFLD, such as insulin resistance, oxidative stress, pro-inflammatory cytokines, apoptosis, bacterial overgrowth, and angiotensin pathway. This lecture aims to show the potential of Tocotrienols as a promising therapeutic option for NAFLD. This is a Systematic Review of the effects of Tocotrienols on Non-Alcoholic Fatty Liver Disease. (NAFLD). Tocotrienols may yet prove to be an effective treatment for Non-Alcoholic Fatty Liver Disease

Biography :

E-mail:

genemapmd@yahoo.com