Konstantinos N Syrigos, Muhammad Wasif Saif, Preethi K John, Andromachi S Kougioumtzopoulou
Ampullary carcinomas are rare malignancies representing less than 1% of all gastrointestinal cancers. Given the lowincidence rate, there is scarcity of data regarding the survival benefit of the treatment options available. In the 2014 ASCOGastrointestinal Cancers Symposium there were two abstracts that discussed the role of pancreaticoduodenectomy andadjuvant radiation therapy in ampullary carcinoma. The first study (Abstract #366) demonstrated a decline in morbidity andmortality over time for pancreaticoduodenectomy making it a reasonable option for successful treatment of ampullarycarcinoma. The second study (Abstract #282) showed that adjuvant radiation therapy in patients with T2 tumors hadimproved median survival times compared to patients that did not receive radiation therapy.
