Pediatrics & Health Research Open Access

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Maternal risk factors associated with retinopathy of prematurity among patients in East Avenue Medical Center from 2010 to 2015

14th World Congress on General Pediatrics & Adolescent medicine
September 25-27, 2017 Chicago, USA

Ida Fidelis Denosta and Carina Cruz-Quimbo

East Avenue Medical Center, Philippines

Posters & Accepted Abstracts: Ped Health Res

Abstract:

Objectives: This study aims to determine the maternal risk factors associated with the development of retinopathy of prematurity (ROP). Patients: This study included admitted premature neonates in neonatal intensive care unit (NICU) who underwent ROP screening. All patients with congenital abnormality of the eyes were excluded in the study. Methodology: This study was done in a tertiary government hospital. The list of admitted premature patients who underwent ROP screening was collected within the study period. Demographic data was collected from the patientâ�?�?s medical records. Statistical Analysis: Descriptive statistics were presented for categorical outcome measures. Wilcoxon rank sum test was used to compare two averages. Chi-square test, Yatesâ�?�? chi-square test and Fisherâ�?�?s exact test were used to compare proportions. Univariate and multivariate regression analyses were used to estimate crude and adjusted odds-ratios, corresponding 95% CI and based on p-value â�?¤ 0.05 statistical significance. Result: This study showed 57% cases of ROP, majority with Stage 1 (66%), mostly female infants (53.4%, p<0.001), mildly asphyxiated (51.2%, p=0.290, 77.2%, p=0.117) and were small for gestational age (57.3%, p<0.001). On the average, these infants underwent 1 day of either invasive or non-invasive mechanical ventilation, 2 days with FiO2 of >0.5 litres per minute, had two blood transfusions, and with shorter hospital stay (17 vs 26 days; p<0.001). The average age of mothers who delivered infants with ROP was 26 years old, multipara (59.2%), and underwent normal spontaneous delivery (67%). About half reported adequate prenatal check-ups (53.8%), and diagnosed with urinary tract infection (40.1%). Conclusion: Data showed that mothers with urinary tract infection and preeclampsia are more likely to deliver infants with retinopathy of prematurity thus significant maternal risk factors of ROP.