Pediatrics & Health Research Open Access

Incidence and predictors of diabetic Ketoacidosis among diabetes children at east and west gojjam zone referral hospitals, north west ethiopia, 2019

International Virtual Congress on Pediatrics

July 07, 2021 | Webinar

Birtukan Assefa, Haymanot Zeleke , Mrs. Rajalakshmi Murugan and Kalkidan Wondwossen

School of Nursing, College of Health Sciences, Debremarkos University, Debremarkos, Ethiopia
school of Nursing and Midwifery, College of Allied Health Sciences, Addis Ababa University, Addis Ababa,1 Ethiopia

: Pediatrics & Health Research

Abstract:

Background Recurrent diabetic ketoacidosis in patients with known diabetes mellitus remains a relevant problem in paediatrics with an incidence of 1–10% per patient. It has a significant mortality (24%) and morbidity (35%) Death is majorly due to cerebral edema Objective We assessed the incidence and predictors of diabetic ketoacidosis among diabetes children at East and West Gojjam zone referral hospitals, North West Ethiopia, 2019. Methods An institution-based retrospective follow up study was conducted on children who were registered from January 1, 2014, to January 1, 2019. Epi data version 3.1 & Stata 14 were used for data entering and analysis respectively Result 01 Out of 354 children included in the study, 207 (58.5%) developed diabetic ketoacidosis. The overall incidence rate of diabetic ketoacidosis was 2.27/100 children/month of observation. Result 02 Age < 5 years (AHR: 3.52, 95% CI (2.25, 5.49) Non-adherence (AHR: 1.54, 95% CI (1.11, 2.14) inappropriate insulin storage (AHR: 1.36, 95% CI (1.008, 1.85) Presence of upper respiratory tract infections during diabetic ketoacidosis diagnose (AHR: 2.22, 95% CI (1.11, 4.45) Preceding gastroenteritis (AHR: 2.18, 95% CI (1.07, 4.44) were significant predictors Conclusion 01 • High incidence of Diabetic ketoacidosis was observed • The significant predictors were • Age < 5 years old, • non-adherence, • inappropriate insulin placement at home, • preceding gastroenteritis, and • presence of upper respiratory tract infections at the time of diabetic ketoacidosis development. Conclusion 02 Hence, assessing and close monitoring as well as strengthened diabetic education should be given for patients with the above predictors.