Chenglong Zhang, Tianyi Long, Fengjuan Li, Fei Li, Liming Peng, Ke Xia, Qiying Xie and Tianlun Yang
Xiangya Hospital Central South University, China .
Posters & Accepted Abstracts: Interv Cardiol J
Background: Dual antiplatelet therapy (DAPT) score and PRECISE-DAPT score have good ability of discriminating the risk of thrombosis and bleeding and were recommended for making optimized antithrombotic strategies. But the relationship between DAPT score and PRECISE-DAPT score with the extent of coronary stenosis has not been established.
Methods: We retrospectively collected the information of 359 patients of acute coronary syndrome (ACS) who received coronary angiography (CAG) and subsequent percutaneous coronary intervention (PCI). DAPT score and PRECISE-DAPT score were calculated and patients were divided by recommended cut-off values (2 for DAPT score and 25 for PRECISE-DAPT score). Gensini score system and triple-vessel disease (3-VD) were chosen to evaluate the severity of coronary stenosis.
Results: Overall, 54.9% and 10.0% of the patients had higher DAPT score or PRECISE-DAPT score. Patients with higher DAPT score had increased stent counts, total length of stents, higher Gensini score and risk of 3-VD, while had decreased minimum diameter of stent. But these differences were not found in PRECISE-DAPT subgroups. However, both DAPT score and PRECISE-DAPT score were independent risk factors of Gensini score after adjusting for baseline factors (p<0.001 and p=0.047). Furthermore, an increase of one point of DAPT score and five points of PRECISE-DAPT score resulted by 89% (p<0.001) and 46% (p=0.04) increase of risk of 3-VD after adjustment.
Conclusion: Both DAPT score and PRECISE-DAPT score were closely and positively associated with the degree of coronary arteriostenosis in patients with ACS.
E-mail:
Chenglongzhang@csu.edu.cn
Spanish 
Chinese 
Russian 
German 
French 
Japanese 
Portuguese 
Hindi 