Journal of Neuro-Oncology and Neuroscience Open Access

  • ISSN: 2572-0376
  • Journal h-index: 5
  • Journal CiteScore: 0.38
  • Journal Impact Factor: 0.36
  • Average acceptance to publication time (5-7 days)
  • Average article processing time (30-45 days) Less than 5 volumes 30 days
    8 - 9 volumes 40 days
    10 and more volumes 45 days
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Valentin Gudumac

Department of Biochemistry, Nicolae Testemi?anu State University of Medicine and Pharmacy, Moldova

Publications
  • Research Article   
    Culture Insights of Cellular Mechanisms of Glioblastomas Growth
    Author(s): Valerii Matcovschii, Valentin Gudumac, Dan Lisii* and Lilia Andronache

    At present, glioblastomas of the brain are incurable tumours and the new developments of clinical neurosurgery, radiation therapy and chemotherapy do not solve the issue. Studying the cellular and subcellular growth mechanisms of the initial glioblastoma cells taken from tumours during neurosurgery and cultivating said cells for 3-6 months, allows us to put forward a relatively new hypothesis about the amitotic division of the glioblastoma cells. It is important to note that the tumour growth occurs via the transfection and expression of fragments of proteins and nucleic acids produced by the glioblastomas into the healthy contractile glial cells. This hypothesis is indirectly confirmed by conducing experimental studies with the introduction into the cell culture of polymerase, adenovirus of the AstraZeneca vaccine, as well the visual data obtain during magnetic resonance ima.. View More»

    DOI: 10.21767/2572-0376.22.7.52

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