Quality in Primary Care Open Access

Department of Chemical and Biological Sciences, Mariano Gálvez University of Guatemala, Guatemala City, Guatemala

Publications

• Research Article   
  Use of Biochemical Biomarkers to Evaluate the Role of Oxidative Stress in the Progression of COVID-19 Severity
  Author(s): Luis Marcano-Marcano* and Raquel Salazar-Lugo
  
  The role of oxidative stress and the use of biochemical biomarkers in the severity of COVID-19 was evaluated through a literature review (2020–2021) using scientific search engines such as PubMed, Science Direct, and Google Scholar. The search was limited to articles published in Spanish or English that reported on COVID-19 and its relationship with oxidative stress, following PRISMA-2020 guidelines. The search terms included oxidative stress, COVID-19, SARS-CoV-2, oxidative biomarkers, and oxidative damage. 93.5% of the selected studies were from the year 2021. These studies evaluated both oxidative stress biomarkers and oxidative damage biomarkers in COVID-19 patients. The reviewed studies reinforce the strong association of SARS-CoV-2 with oxidative stress and demonstrate how SARS-CoV-2 induced ROS production and disruption of the antioxidant defense system trigger a pro-infl.. View More»
  

  Abstract PDF