Department of Biology, Hassan II University of Casablanca, Casablanca, Morocco
Research Article
Evaluation of Ketoprofen Effect on Oxidative Stressed Mice
Author(s): Benkhassi Zoubair*, Loutfi Mohammed, Benaji Brahim, Mostafa kabine and Bourhim Noureddine
Ketoprofen one of the propionic acid classes of Nonsteroidal Anti-Inflammatory Drugs (NSAID) with
analgesic and antipyretic effects. It acts by inhibiting the body's production of prostaglandin it was
patented in 1967 and approved for medical use in 1980. Ketoprofen is widely used for the treatment
of pains, fever and inflammation is generally prescribed for arthritis related inflammatory pains or
severe toothaches that result in the inflammation of the gums. Ketoprofen topical patches are being
used for treatment of musculoskeletal pain. This study designed to evaluate if Ketoprofen has
an antioxidant effect, relative to its analgesic, antipyretic and anti-inflammatory activities.
Oxidative stress was induced by intraperetoneal injection of Hydrogen Peroxide (H2O2), and then a
comparative study is made concerning the activities of the ant.. View More»
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