Department of Organic Chemistry, Suez Canal University, Ismailia, Egypt
Research Article
The Role of Human Tumor Necrosis Factor-α (TNF-α) in Predicting Diabetic Nephropathy in Type ? Diabetic Patients
Author(s): Khalid Ibrahem Husein Al Ghodran*, Amina Ali Dessouki, Heba MA Abdelrazek, Dahlia Ibrahim Badran and Emad M Gad
Background: Diabetic nephropathy is a chronic main microvascular consequence of untreated hyperglycemia, affects a significant portion of the population. It's thought to be the main factor causing end-stage kidney disease. Proinflammatory cytokine TNF-α is involved in the development and course of disease in diabetic nephropathy.
Aim: This study aimed at the detection the validity of using tumor necrosis factor-alpha as earlier and reliable biomarker for diabetic nephropathy.
Materials and methods: This study included 125 Egyptian subjects attending the out patients clinic of the Department of Internal Medicine, 10th of Ramadan City Health Insurance Hospital and divided as follow Group A: Control group which included 20 healthy subjects. Study groups: Included 105 patients divided into three sub-groups: .. View More»
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