Commentary - (2022) Volume 6, Issue 12
Received: 30-Nov-2022, Manuscript No. IPJCGH-23-15586; Editor assigned: 02-Dec-2022, Pre QC No. IPJCGH-23-15586 (PQ); Reviewed: 16-Dec-2022, QC No. IPJCGH-23-15586; Revised: 21-Dec-2022, Manuscript No. IPJCGH-23-15586 (R); Published: 28-Dec-2022, DOI: 10.36648/2575-7733.6.12.57
The growth of liver fat in those who drink little to no alcohol. What causes non-alcoholic fatty liver disease is unknown NAFLD. Risk factors include type 2 diabetes, high cholesterol, gastric bypass surgery, and obesity. Most individuals don’t exhibit any symptoms. Sometimes people may feel worn out, in pain, or lose weight. In cirrhosis, the liver over time develops scarring and inflammation. There isn’t a set course of treatment. Instead, health care providers will deal with the underlying issue, such as obesity.
Non-alcoholic fatty liver disease (NAFLD) is the name given to a set of illnesses in which persons who use little or no alcohol develop excess liver fat. The most typical form of Non-alcoholic fatty liver disease is fatty liver, a benign disorder. In fatty liver, fat deposits accumulate in the liver cells. Despite the fact that liver fat is abnormal, it is likely not harmful to the liver on its own. Some NAFLD patients may also have Non-alcoholic Steatohepatitis (NASH), a more severe illness. Inflammation of the liver cells and varying degrees of scarring are related to fat buildup in NASH. Non-alcoholic Steatohepatitis has the potential to cause cirrhosis and severe liver scarring, which might be life-threatening. Cirrhosis develops when the liver suffers considerable injury and the liver cells are gradually replaced by scar tissue, impairing the liver’s ability to function. Some people with cirrhosis may require a liver transplant.
Most NAFLD sufferers don’t exhibit any symptoms and appear healthy from the outside. Fatigue and abdominal pain, which may be in the centre or right upper section of the belly, are common in children. However, there are more possible reasons of stomach pain and exhaustion. On inspection, the liver may appear somewhat larger in some kids with acanthosis nigricans, a patchy, dark skin discoloration that most frequently affects the neck and underarm region.
The metabolic syndrome, which includes NAFLD, is characterised by diabetes or pre-diabetes (insulin resistance), obesity, raised blood lipids like cholesterol and triglycerides, and high blood pressure. Not every patient with the metabolic syndrome exhibits all of its symptoms. There is limited knowledge on the origins of Non-alcoholic Steatohepatitis development. Numerous factors that are now the subject of investigation may have an impact on how Non-alcoholic Steatohepatitis develops.
Non-Alcoholic Fatty Liver Disease is a condition that affects as many as one in three to one in five people and one in ten children in the United States. Obesity is regarded to be the main cause of fat infiltration of the liver. According to some estimation, fatty liver may be present in about two thirds of obese adults and half of obese children. Up to 20% of obese people in America may have the more severe illness known as Non-alcoholic Steatohepatitis, which may impact 2% to 5% of adult Americans. The number of children that have Non-alcoholic Steatohepatitis is unclear. Type 2 diabetes and other disorders connected to insulin resistance, such as polycystic ovarian syndrome, are known to affect the development of fatty liver and Non-alcoholic Steatohepatitis.
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Author declares that there is no conflict of interes
Citation: Gomez E (2022) Non-Alcoholic Fatty Liver Disease (NAFLD) and its Major Causes. J Clin Gastroenterol Hepatol. 6:57.
Copyright: © 2022 Gomez E. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
