Kshitij Kumar*
The nose-to-brain drug delivery system has emerged as a promising approach for the targeted delivery of therapeutics to the Central Nervous System (CNS). This non-invasive and efficient method bypasses the blood-brain barrier, allowing drugs to reach the brain directly through the olfactory and trigeminal pathways. This abstract provides an overview of the key advancements and applications of the nose-to-brain drug delivery system. Recent developments in nanotechnology, such as nanoparticles and liposomes, have enabled the encapsulation of various drugs, including neuroprotective agents, peptides, and small molecules, for precise delivery to the brain. These advancements have opened new possibilities for the treatment of neurodegenerative diseases, brain tumors, and neurological disorders. Furthermore, the nose-to-brain route offers advantages such as rapid onset of action, reduced systemic side effects, and improved patient compliance. It has found applications in the treatment of Alzheimer's disease, Parkinson's disease, migraine, and epilepsy, among others. This abstract highlight the potential of the nose-to-brain drug delivery system as a valuable tool in neuropharmacology and neuroscience research, offering hope for more effective treatments for a wide range of Central Nervous System (CNS) related conditions. However, further research is needed to optimize delivery strategies, ensure safety, and maximize therapeutic outcomes in clinical settings.
Published Date: 2025-01-18; Received Date: 2023-11-11
