Julio César Gutiérrez-Segura*, Daniela Velásquez López, Juan Pablo Abad Salazar, Yuli Meneses Meza, Tania Camila Muñoz Obregón, Isabella Acevedo Zuluaga, Angela Maria Landázury
Secondary mania is characterized by the sudden onset of symptoms without a prior history of affective disorders, manifesting as elevated mood, irritability, and insomnia. Brain tumors are the eighth most common type of cancer in adults over 40 years of age, with gliomas being the most prevalent malignant histology, presenting with symptoms such as headache, seizures, and cognitive impairment. We present the case of a patient in her seventies who experienced progressive symptoms, including irritability, sleep disturbances, increased motor activity, and delusional as well as jealous delusions. Initially diagnosed with bipolar disorder and treated without improvement, her condition deteriorated with persistent headaches and worsening of symptoms. Upon initial evaluation at Hospital Universitario San Jorge, she exhibited aphasia and affective exaltation, and neuroimaging revealed a space-occupying lesion in the left temporal region. After neurosurgical evaluation, a probable diagnosis of glioblastoma was established, and she underwent surgery.
Published Date: 2025-01-24; Received Date: 2024-08-17
