International Journal of Applied Science - Research and Review Open Access

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Incidence of Neoplastic Cervical Pathologies Recorded at a Medical College

Purnima Poste

Objective: The present study was undertaken for a period of three years (from June 2008 to May 2011), to study the epidemiology of neoplastic cervical lesions recorded at a Pathology Department and allied centers at a Medical College.

Methods: The period of study from June 2008 to May 2009 was retrospectives and from June 2009 to May 2011 was prospective.

Results and Conclusion: In this study total 1260 cervical specimens were studied, of which 13% were malignant. Benign cervical lesions and cervical intraepithelial neoplasia constituted 6.19% and 4.04% respectively. Total number of benign lesions were 78 (6.19%), of which endocervical polyp were most common (59 cases or 77.63%), followed by leiomyomatous polyp (22.37%). The age range was 30-50 years. Endocervical polyps were most commonly detected in patients diagnosed with cervical polyp, DUB, or ovarian cyst. Leiomyomatous polyps were commonly detected in patients with fibroid uterus. The total number of cervical intraepithelial lesions were 51 cases (4.04%), of which 15 were CIN I (29.4%), 25 were CIN II (49.01%), and 11 were CIN III (25.49%). The common age group was 30-40 years and 40-50. They were commonly presented with irregular vaginal bleeding and foul smelling white discharge per vaginum. A total of 164 invasive malignancies were encountered (13.01%). Squamous cell carcinoma was the commonest invasive carcinoma (157cases or 95.73%). The youngest patient was 29 years and oldest 82 year. The peak incidence was in the 4th and 5th decades. Metrorrhagia and foul smelling white discharge was most common symptom in patients diagnosed with carcinoma. Further, squamous cell carcinoma was the commonest histological subtype noted with large cell non keratinizing carcinoma (97 cases or 61.7%) followed by large cell keratinizing type (48 cases or 30.5%) and small cell non keratinizing type (6 cases or 3.82%). In a few patients, adenocarcinoma, adenosquamous carcinoma and neuroendocrine carcinoma were also recorded.