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Abstract

Evaluation of the Relationship between ADHD and Comorbid Psychiatric Conditions: A Comprehensive Study on a Large Cohort

Adeel Sarwar* and Frank Vitetta

This study delves into the psychiatric complexities accompanying Attention-deficit or Hyperactivity Disorder (ADHD), scrutinizing the prevalence and nature of comorbidities amid diverse gender categories, including transgender and non-binary individuals. Under the expert guidance of MD Adeel Sarwar, this research examined data from 1,528 participants collected via the ADHDtest.ai website, employing standardized diagnostic tools to delineate ADHD and concurrent psychiatric conditions.

A stark prevalence of anxiety disorders was noted, particularly in non-binary (63.2%) and transgender individuals (37.5%). This point towards a dire need for specialized healthcare provisions catering to these populations. The anal- ysis also unveiled a notable pattern: 44.97% of females with an ADHD diagnosis did not report pre-existing condi- tions, marking a unique presentation of ADHD within this group. These findings underscore the complexity of ADHD as it intertwines with other conditions, necessitating gender-specific considerations in both diagnostic frameworks and treatment modalities.

Mirroring the National Institute of Mental Health’s stance on ADHD comorbidity, the study underscores an impera- tive for adopting a multifaceted evaluative approach to bolster clinical outcomes. This research expands our under- standing of ADHD’s intricate psychiatric landscape, pressing the need for further studies into its comorbid disorders and the impacts these have on individualized treatment strategies.

Contrasting with Caye et al. (2016) study, which was contingent on the assumption that adult ADHD must originate in childhood, this investigation adopts a gender-inclusive lens to challenge long-standing diagnostic norms. The pri- or study, utilizing the 1993 Pelotas Birth Cohort Study, tracked 5,249 Brazilian youths into young adulthood (18-19 years), aligning with DSM-5 criteria to identify ADHD symptoms both in childhood and adulthood, and acknowl- edged a distinct trajectory for the disorder beyond childhood. In comparison, our current study, engaging a cohort primarily from the USA, UK, and Canada, broadens the demo- graphic focus and reaffirms the nuanced gender distribution-observing a male predominance in childhood ADHD diagnoses versus a female predominance in young adulthood. This investigation reinforces the perspective that adult ADHD may represent a divergent developmental path, not solely an extension from childhood, and supports the hypothesis of distinct ADHD trajectories across life spans.

Published Date: 2023-10-30; Received Date: 2023-11-09