Kristian Alda, M Adya F Dilmy* and Hariyono Winarto
Cervical cancer is one of the most common malignancies affecting women worldwide, but its occurrence during pregnancy remains rare, affecting only 1%-3% of pregnant women. Managing cervical cancer in pregnancy poses significant clinical and ethical challenges, as treatment must balance maternal oncologic outcomes with fetal safety. We report a case of a 38-year-old woman, gravida 3 para 2, diagnosed with stage IB1 cervical squamous cell carcinoma at 30 weeks of gestation, who presented with postcoital bleeding and lower abdominal pain. Clinical, ultrasound, and MRI assessments revealed a 2 cm cervical mass without evidence of local invasion or lymphadenopathy. Histopathology confirmed moderately differentiated non-keratinizing squamous cell carcinoma. Respecting the patient’s strong desire to continue the pregnancy, a multidisciplinary team opted for delayed treatment. After fetal lung maturation, cesarean section was performed at 36 weeks followed by radical hysterectomy with left salpingo-oophorectomy and right ovarian transposition. The neonate, delivered with transient respiratory complications, was managed in the neonatal intensive care unit. Postoperative recovery was stable, and adjuvant chemoradiation was planned. This case highlights the importance of individualized care, taking into account gestational age, tumor characteristics, and patient preferences. In select early-stage cervical cancer cases, deferred definitive treatment until fetal maturity followed by radical surgery may offer favorable outcomes for both mother and fetus.
Published Date: 2025-08-18; Received Date: 2025-07-18
