End stage renal diseases patients mostly undergo kidney or renal transplantation. It is a procedure to put a healthy kidney inside the human body or a recipient body. Here two types of donors are present first is a living donor who is anyone from family, friend circle, colleague or any person who is willing to give a kidney to save life. Another donor is deceased donor who is recently died. This kind of surgery is preferred to avoid dialysis as well as longer survival of a patient. Several risks are also involved in this such as bleeding, severe infection, new kidney rejection, reaction to the anaesthesia used during surgery, failure of the donor etc. To avoid problem of new kidney rejection a patient must prescribed with the immunosuppressant’s eg cyclosporine , tacrolimus etc. This kind of transplantation does not give any guarantee of longer life that one can have without new kidney.