Pancreas transplantation is the transfer of a healthy pancreas from donor to patients with diabetes. Since pancreas is a vital organ, the patient′s native pancreas is left in place, and the donated pancreas is placed in a different location. This is done because in case of rejection of the new pancreas, the patient will develop severe diabetes and he would not survive without the native pancreas still in place. The healthy pancreas comes from a donor who has just died or from a brain dead person. At present, pancreas transplants are commonly done in persons with severe insulin-dependent diabetes.