Replication is the process to make new copies. The HIV virus only replicate in human cells. The HIV replication process carrying seven steps, the steps are entry, reverse transcription, integration, transcription, translation, assembly, release and maturation. This replication process starts with enter into a cell, it carry’s special protein called CD4.after entering of the cell reverse transcriptase enzyme converts viral RNA to DNA. It is transferred through the nucleus then; it is inserted in to human DNA by HIV integrase enzyme. After insertion this DNA called as provirus. The pro virus enter into cell, the cell was activated it converts into messenger RNA by using human enzymes. After that the mRNA transfers to outside the nucleus the enzyme protease mature new virus particles.