Green synthetic route to access functionalized bio-active organic scaffolds using tetragonal nano-ZrO2 as reusable solid acid catalyst

Arijit Saha; Subhash Banerjee

doi:10.21767/2471-9889-C1-003

Green synthetic route to access functionalized bio-active organic scaffolds using tetragonal nano-ZrO2 as reusable solid acid catalyst

Joint Event: 5^th International Conference on Green Chemistry and Technology & 6^th International Conference on Environmental Chemistry and Engineering

July 24-26, 2017 Rome, Italy

Arijit Saha and Subhash Banerjee

Guru Ghasidas Vishwavidyalaya, India

Posters & Accepted Abstracts: Trends in Green chem

Abstract:

Over past decades, one-pot multicomponent reactions (MCRs) have been established as one of the important synthetic tool for the synthesis of bio-active organic scaffolds. As a part of our interest to develop green and efficient multicomponent protocol, we have demonstrated the role of nanoparticles (NPs) in MCRs in determining the selectivity and performance of the protocol. In this presentation, the role of ZrO2 NPs in one-pot MCRs leading to fabrication of bio-active organic moieties such as, benzylpyrazolyl coumarin (I), pyrano[2,3-c]pyrazole (II), coumarin fused 4H-chromene (III) and 2-amino-chromene (IV), derivatives will be presented. In addition, the effect of phase (tetragonal/monoclinic/cubic), surface defect and size of the NPs as well as effect of solvent on the rate of the reaction will be discussed. We observed that the ZrO2 NPs can be recycled up to ten times without any notable change in catalytic activity and morphology.