Commentary - (2022) Volume 7, Issue 11
Received: 01-Nov-2022, Manuscript No. IPIB-22-15048; Editor assigned: 03-Nov-2022, Pre QC No. IPIB-22-15048(PQ); Reviewed: 17-Nov-2022, QC No. IPIB-22-15048; Revised: 22-Nov-2022, Manuscript No. IPIB-22-15048(R); Published: 29-Nov-2022, DOI: 10.36648/2572-5610.22.7.109
The emerging field of biomedical application of nanoparticles (NPs) relies heavily on Electron Microscopy (EM) to locate NPs within the cellular envelope. EM can monitor and quantify NP dispersion, dissolution, and dose internalized by cells and tissues, but this will only be accurate with the right sample preparation. The resolution of the cellular ultrastructure must be taken into account when preparing cellular material for EM, and target NPs must not be significantly altered or lost. The coordination of live organic entities into micro fabrication processes sets out many invigorating open doors. First, extensive research on large specimen sets is common in biomedical research on small organisms like Drosophila and Caenorhabditis elegans. Utilizing micro-fabricated devices allows for the improvement or even omission of individual organism handling steps. Second, a number of biological organisms possess desirable characteristics that cannot be replicated synthetically. The direct utilization of these capabilities for unique biomedical applications is made possible through hybrid system development. The National Institutes of Health (NIH) Common Fund provides funding for the Cellular Senescence Network (SenNet), which is managed in conjunction with the National Institute on Aging and National Cancer Institute. SenNet will create a 3D body map that is navigable and coordinated by scientists in Pittsburgh. It will provide information and analysis on cellular aging, shedding light on nerve degeneration, diabetes, cancer, and normal tissue functions. According to Draper and Wells, a side-injected micro-LED platform has the potential to be used in other biomedical applications, such as the management of pain and injury through photobiomodulation in sports medicine and well-being. As was demonstrated, the guiding membrane, which is made of PDMS, is suitable for total internal reflection fluorescence sensing because it also lends itself to the integration of fluidics. The Biomedical Applications Group is actively involved in medical technology development. Diagnostics and therapeutic devices, rehabilitation and assistive technologies for the elderly and differently abled, imaging-based medical devices, and advanced manufacturing-based orthopaedic and dental implants are the primary focus areas in this important area of research and development at CSIO. The Biomedical Applications Group is actively involved in medical technology development. Diagnostics and therapeutic devices, rehabilitation and assistive technologies for the elderly and differently abled, imaging-based medical devices, and advanced manufacturing-based orthopaedic and dental implants are the primary focus areas in this important area of research and development at CSIO. A small micro-LED patch that could be worn as a biosensor is already possible. The application of engineering and technology to living things, particularly in the creation and use of medical equipment. Find out more. An overview of intra-body communication transceivers for use in biomedical applications. There are currently a wide variety of EM imaging modes that possess the necessary spatial resolution and sensitivity to measure and quantify the position and number of NPs in a biological matrix. Analytical EM also makes it possible to quantify the NP composition and ionic content of intracellular compartments. For physical and biological scientists, these methods blur the traditional distinctions between EM and scanning and transmission. The purpose of this chapter is to provide a summary of how EM can be used to analyse NPs in cells and tissues, as well as a brief discussion of how it relates to live cell imaging.
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The author’s declared that they have no conflict of interest.
Citation: Hosokawa C (2022) Study of Biomedical Engineering Application and their Usage. Insights Biomed. 7:109.
Copyright: © 2022 Hosokawa C. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
