Journal of Intensive and Critical Care Open Access

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Opinion - (2023) Volume 9, Issue 4

Relationship between Glycaemic Control Parameters and Clinical Outcomes in Chronic Critical Illness
Judith E Nelson*
Department of Medicine, University of Mount Sinai, USA
*Correspondence: Judith E Nelson, Department of Medicine, University of Mount Sinai, USA, Email:

Received: 01-Aug-2023, Manuscript No. IPJICC-23-17774; Editor assigned: 03-Aug-2023, Pre QC No. IPJICC-23-17774 (PQ); Reviewed: 17-Aug-2023, QC No. IPJICC-23-17774; Revised: 22-Aug-2023, Manuscript No. IPJICC-23-17774 (R); Published: 29-Aug-2023, DOI: 10.35248/2471-8505-9.4.37


Chronic critical illness is a complex medical condition characterized by a prolonged state of severe illness, often requiring Intensive Care Unit (ICU) support for an extended period. It affects individuals who experience a persistent and significant impairment of organ function and require ongoing medical intervention. Understanding the symptoms of chronic critical illness is crucial for early recognition, appropriate management, and improved patient outcomes. In this article, we delve into the various symptoms associated with chronic critical illness and explore their impact on patients’ lives. Respiratory dysfunction is a hallmark of chronic critical illness. Patients often experience persistent shortness of breath, difficulty breathing, and decreased exercise tolerance. They may require prolonged mechanical ventilation or assistance with breathing, such as tracheostomy. Chronic respiratory symptoms can significantly limit physical activities, leading to reduced quality of life and increased vulnerability to infections. Chronic critical illness can affect the cardiovascular system, resulting in symptoms such as persistent low blood pressure (hypotension), rapid heart rate (tachycardia), and decreased cardiac output. Patients may experience dizziness, fatigue, and fluid retention, contributing to the development of conditions like heart failure. The compromised cardiovascular function in chronic critical illness can have significant implications for overall health and may require close monitoring and medical interventions.


Neurological manifestations are common in chronic critical illness. Patients may exhibit confusion, cognitive impairment, memory deficits, and delirium. These symptoms can arise due to various factors, including medications, infections, and the underlying critical illness itself. The neurological consequences of chronic critical illness pose challenges in communication, decision- making, and rehabilitation, affecting both patients and their caregivers. Prolonged immobility and muscle weakness are prevalent in chronic critical illness. Patients may experience muscle wasting (atrophy) and joint stiffness due to extended bed rest and limited physical activity. This can lead to decreased mobility, difficulty with basic tasks, and a higher risk of falls. Rehabilitation and physical therapy are essential components of managing musculoskeletal symptoms in chronic critical illness to improve strength and functional independence. Chronic critical illness often leads to nutritional deficiencies and weight loss. Patients may experience reduced appetite, difficulty swallowing (dysphagia), and altered taste sensations. Inadequate nutrition can further exacerbate muscle wasting, compromise immune function, and impair wound healing. Nutritional support, the psychological impact of chronic critical illness is substantial. Patients often experience anxiety, depression, Post-Traumatic Stress Disorder (PTSD), and adjustment disorders. The emotional toll of prolonged illness, combined with the challenging ICU environment, can lead to feelings of helplessness, isolation, and emotional distress.


Psychological support, counselling, and rehabilitation programs can play a vital role in addressing these symptoms and promoting mental well-being. Chronic critical illness makes individuals susceptible to infections, particularly in the ICU setting. Symptoms of infections can vary based on the site and type of infection but commonly include fever, chills, increased heart rate, and respiratory distress. Pneumonia, bloodstream infections, urinary tract infections, and surgical site infections are frequently observed in these patients. Chronic critical illness is a multifaceted condition that affects multiple organ systems and presents with diverse symptoms. Recognizing and addressing these symptoms promptly are pivotal in improving patient outcomes and enhancing quality of life.

Citation: Nelson JE (2023) Relationship between Glycaemic Control Parameters and Clinical Outcomes in Chronic Critical Illness. J Intensive Crit Care. 9:37.

Copyright: © 2023 Nelson JE. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.