Journal of Prevention and Infection Control Open Access

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Opinion - (2023) Volume 9, Issue 3

Acute Flaccid Myelitis: An Emerging Neurological Challenge
Carl George*
Department of Science, University of California, USA
*Correspondence: Carl George, Department of Science, University of California, USA, Email:

Received: 30-Aug-2023, Manuscript No. IPJPIC-23-17936; Editor assigned: 01-Sep-2023, Pre QC No. IPJPIC-23-17936 (PQ); Reviewed: 15-Sep-2023, QC No. IPJPIC-23-17936; Revised: 20-Sep-2023, Manuscript No. IPJPIC-23-17936 (R); Published: 27-Sep-2023, DOI: 10.36648/2471-9668-9.3.22


Acute Flaccid Myelitis (AFM) is a rare but alarming neurological disorder that predominantly affects children and can result in sudden paralysis. This research article provides an in-depth examination of AFM, including its clinical presentation, epidemiology, potential causes, diagnosis, treatment options, and ongoing research efforts to understand and combat this emerging health challenge. Acute Flaccid Myelitis (AFM) is a relatively rare but concerning neurological condition characterized by the sudden onset of limb weakness, often accompanied by loss of muscle tone and reflexes. The term “acute” underscores the rapid progression of the condition, with potentially devastating consequences. Although AFM is relatively uncommon, it has garnered significant attention from the medical and scientific communities due to its association with clusters of cases in different regions, typically affecting children. AFM first gained significant attention in 2014 when a noticeable spike in cases occurred in the United States, coinciding with an outbreak of respiratory infections caused by enterovirus D68 (EV-D68). While the number of cases has varied from year to year, AFM tends to be a seasonal illness with a peak in late summer and fall. The reasons behind these outbreaks remain a subject of ongoing investigation. The exact cause of AFM remains elusive, but it is widely believed to be linked to viral infections. Enteroviruses, particularly EV-D68 and EV-A71, are often implicated. However, not all cases of AFM are associated with a known viral infection, and the precise mechanism by which these viruses may trigger the condition is not fully understood. Diagnosing AFM is challenging, as its clinical presentation overlaps with other neurological disorders. To confirm a diagnosis, healthcare professionals typically rely on a combination of clinical history, physical examination, magnetic resonance imaging (MRI) of the spinal cord, and cerebrospinal fluid analysis. It is essential to rule out other potential causes of limb weakness and paralysis. Unfortunately, there is no specific antiviral treatment for AFM, and management primarily involves supportive care to address the symptoms. Physical and occupational therapy, as well as rehabilitation, are essential for affected individuals to regain lost function and improve their quality of life. In severe cases, ventilatory support may be necessary to address respiratory distress.


Researchers and healthcare professionals are actively working to better understand AFM. Ongoing studies aim to elucidate the role of enteroviruses in the development of the condition, identify potential risk factors, and improve diagnostic criteria. Moreover, the development of antiviral therapies and potential vaccines against implicated viruses remains a priority. The exact causes of Acute Flaccid Myelitis (AFM) remain the subject of on-going research, and while several factors have been implicated, a definitive cause has not yet been established. AFM is believed to be associated with various viruses, with enteroviruses being the primary suspects. The following factors and associations are currently under investigation. In addition to enteroviruses, other viruses, such as West Nile virus, adenoviruses, and coxsackieviruses, have been investigated as potential triggers for AFM. These viruses can cause a wide range of neurological symptoms, including inflammation of the spinal cord.


Acute Flaccid Myelitis is a rare but concerning neurological disorder primarily affecting children. Its association with viral infections and the rapid onset of paralysis makes it a significant public health concern. Continued research is needed to elucidate the underlying causes and develop effective treatments for this condition. As our understanding of AFM continues to evolve, healthcare providers, researchers, and policymakers must remain vigilant in their efforts to mitigate its impact and improve patient outcomes.



Conflict Of Interest


Citation: George C (2023) Acute Flaccid Myelitis: An Emerging Neurological Challenge. J Prevent Infect Cntrol. 9:22.

Copyright: © 2023 George C. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.