Neurodegenerative diseases area unit one in every of the leading health challenges in trendy medical record due to their intriguing nature and also the lack of information within the understanding of the underlying causes. Recent analysis has helped scientists acquire a larger insight into the cellular, molecular and genetic predispositions of those conditions. The foremost tough side in treating these diseases is that the time needed to create a correct diagnosing, that is sometimes once the sickness has already advanced to a stage of irreparable harm. The studies dispensed within the last fifteen years have helped scientists gain a stronger insight into the molecular and genetic levels of predisposing factors and sickness mechanisms. Once the particular cause and also the pattern of sickness progression area unit discovered, the treatment choices can become additional on the market and effective. RNA metabolism is that the basic method by that RNA is generated, transported, regulated, keep and translated. Recent studies have shown that mutations in RNA-binding proteins area unit a key reason behind many human neural based mostly diseases.