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Total Serum Immunoglobulin√?¬Ę√?‚?¨√?‚?Ęs E Levels in Chemical Industry Workers (SITE Area, Kotri, Jamshoro) Exposed with Organic Acid Anhydrides (OAAs)

Allah Bux Ghanghro, Sumera Qureshi, Sikander Ali Memon and Faisal Qureshi

Objective: Allergy has been a health risk to Organic acid anhydrides (OAAs) exposed workers for many decades. It is one of the most serious public health problems among chemical industry workers of SITE Area kotri, Sindh, Pakistan. Immunoglobulin IgE is an essential antibody responsible for various allergic reactions occur after exposure to harmful chemicals occupationally

Method: In this recent study, Immunoglobulin IgE levels were determined quantitatively in the serum of exposed chemical industry workers (n=45) with comparison to healthy control subjects (n=40).The IgE quantitative test was done by Enzyme linked immunosorbant (ELISA) Kit Method system based on solid phase.

Result: The Serum IgE mean levels of workers determined about 212 IU/L were higher as compared to the 63.3 IU/L in healthy controls.

Conclusion: It is concluded that increased IgE levels leading to mild asthma and other respiratory problems induced by inhalation of Haptens like Organic acid anhydrides(OAAs) in SiteArea,Kotri, workers.