Journal of Infectious Diseases and Treatment Open Access

  • ISSN: 2472-1093
  • Journal h-index: 7
  • Journal CiteScore: 1.06
  • Journal Impact Factor: 0.77
  • Average acceptance to publication time (5-7 days)
  • Average article processing time (30-45 days) Less than 5 volumes 30 days
    8 - 9 volumes 40 days
    10 and more volumes 45 days


The Evaluation of Microbiology in Patients with Fournier?s Gangrene

Agnieszka Grabinska*, Lukasz Michalczyk, Anna Grabinska, Tomasz Syrylo and Tomasz Zabkowski

Introduction: Fournier’s Gangrene (FG) is a devastating necrotising disease that affects the perineum and genitourinary regions. The aim of this study is to identify pathogens whose growth was associated with FG and their antibiotic sensitivity/resistance patterns based on bacterial culture; in addition, this study investigated the relationship between causative pathogens and prognostic factors and mortality.

Materials and methods: It was a retrospective study of 35 patients who were treated for fournier's gangrene in the period from 2017 to 2022. The study group consisted only of male persons (n=35) aged 24-85 years. Demographic data were evaluated and their relationship with causative pathogens, as well as their impact on antibiotic sensitivity and resistance patterns, were investigated.

Results: The most common microbiology involved in FG is polymicrobial infection (54%) and the most common found pathogen isolate is Escherichia coli (32.6%) In the cultures of the gangrene material bacteria were detected: Escherichia coli in 14 (32.6%) people, Enterococcus faecalis in 6 (14%) people and Pseudomonas aeruginosa in 5 (11.6%) people.

Most bacteria were sensitive to piperacillin-tazobactam, clindamycin and metronidazole and resistant to cefuroximum, ciprofloxacin and ceftriaxone.

Conclusions: Causative pathogens in FG are shifting; thus, empirical antibiotic treatment for this disease should be modified.

Published Date: 2023-09-27; Received Date: 2023-08-30