European Journal of Experimental Biology Open Access

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The comparison of WHR and Hs-CRP inflammatory marker in active and inactive middle-aged women

Masoumeh Hosseinnezhad, Mohammad Reza Ramezanpour and Azam Vakili Arki

Cardiovascular diseases and its relationship with physical inactivity have been of interest for many years. Waist-to-hip ratio (WHR) and high-sensitivity C-reactive protein (Hs-CRP) are from independent and warning strong factors of cardiovascular diseases. The purpose of this study was comparing the WHR and Hs-CRP as a predictor of cardiovascular disease in active and non-active middle-aged women. The present research is causal-comparative. 30 women with mean of age: 41/34±3/51 year, height: 158/89±5/136cm, weight: 76/69±4/749 kg, BMI: 27/61±1/96 kg/m2 were participated in this research. They were randomly divided in two groups (active group, n=15, non-active group, n=14). Active group of women who had regular physical activity for one year and non active group who didn`t have any physical activity in last year. In this study, the Kulumogr of-Smirnoff test to assume normality of data and also independent groups T-test was used to compare means (p<0.05).Data analysis showed that there are significant differences in WHR (P=0/003) and the level of serum Hs-CRP (P=0/001) in active and inactive women. Regular physical activity reduces the risk of cardiovascular disease due to its anti-inflammatory effects in middle-aged overweight women.WHR index is also influenced by physical activity, so middle-aged women with weight control and regular exercise can keep the it`s in the normal range.