European Journal of Experimental Biology Open Access

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Study of virulence determinants and antimicrobial activity of drugs against urinary tract infection pathogens

Seema Rawat

The uropathogens possess a wide array of virulence factors which help them in pathogenesis. The present study investigated the virulence factors produced by uropathogens and also determine the antimicrobial activity of drugs against the pathogens. E. coli was documented to be the most prevalent uropathogen. 60% of uropathogens were found to be siderophore producers. 73% isolates were found to be protease producers. A total of 74% uropathogens were rhamnolipid producers. Isolates were found to be maximally sensitive towards streptomycin and oxacillin.