European Journal of Experimental Biology Open Access

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Study effects of ginseng (ginsin) under immobility stress on some blood biochemical parameters on male wistar rats

Masood Khakzadihe, Navid Pashaeian, Sara Aghdasi, Mir Naser Mousavinia, Hossein Dehghan and Seyed Hossein Shahab Zadeh

Ginseng is a highly valued herb in the far east and has gained popularity in the west during the last decade .The ginseng root has been used for over 2000 years, in the belief that it is a panacea and promotes longevity. The Korean herbal medicine, Panax ginseng has been widely used in China and Japan to fight fatigue and for the enhancement of resistance to many diseases. Normal values of biochemical parameters of blood and investigating them and determining changes can assist us in identifying different physiological and pathological states. In this study, the effects of ginseng on some biochemical parameters of rat blood under stress have been studied. For this study, 24 adult male rats were selected. Then the rats were divided into three groups of 8 rats. During the entire period, feeding was performed on the ad libitum basis. In this experiment, the first (group treatment) and second (group ginseng treatment) groups were transferred daily into the Restrainer and were under immobility stress for 2 hours per day during 15 days. For ginseng group, Ginsin 500mg/kg was given daily after immobility stress. The treatment group and control group were given water instead of ginseng by gavage each day. The results of the creatinine, albumin, glucose and amylase did not show any significant differences between groups. There was a significant difference on total protein between treatment group and ginseng treatment group (p<0.05).