Ram Nawal Rao, Ranjana Ranade, Praveer Rai
Context Primary myxofibrosarcoma of the pancreas is a very rare entity. Case Report Myxofibrosarcoma is a rare tumour of mesenchymal origin, composed of malignant fibrocytes in a myxoid matrix. Previously it was known as myxoid malignant fibrous histiocytoma. It usually involves the extremities, followed by trunk, retroperitoneum, mediastinum and head. Based on the degree of cellularity, pleomorphism and mitosis these lesions vary from low-grade to high grade. They have high rate of recurrence but metastasis is very uncommon. Cellblock and histopathology showed a characteristic distinct curvilinear vascular patterns. Conclusion Myxofibrosarcoma is uncommon neoplasm presenting as mucinous cystic mass, possibility of myxofibrosarcoma may be considered on cytology if the smears revealed occasional spindle cells, abundant mucinous and myxoid material in background.
