European Journal of Experimental Biology Open Access

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Measurement of rabbit�?¢�?�?��?�?�s Glomerular Filtration rate (GFR) by Scintigraphy

Vadoud Jabarian, Gholamreza Assadnassab, Shahram Dabiri Oskoi, Reza Habbibipour

Nuclear medicine has been rapid progress in recent decades. In this method, the administration of radioisotopes to the body and accumulation of these substances in the tissues, specific imaging is obtained, which is based on distribution of Gamma radiations exposed from these radioisotopes and recording of them. In this study we aimed to assess the physiological behavior of rabbit’s kidneys by Scintigraphy and the results presented for use in future studies. In present study, six non-pregnant adult apparently healthy rabbits were selected for the attainment of the German race and their racial purity of the whereabouts of the animals was purchased. In our investigation, the mean value of total GFR was 114.01±7.6 ml/min which was consist of right and left kidney’s GFR about 56.05±4.2 and 57.12±4.4 ml/min respectively. There is no significant difference in GFR obtained from right and left kidneys