European Journal of Experimental Biology Open Access

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Incidence of various soft tissue tumours among benign and malignant cases

Reily Ann Ivan, Shameema S. and Sarada V.

Soft tissue can be defined as non epithelial extraskeletal tissue of the body exclusive of the reticuloendothelial system, glia and supporting tissue of various parenchymal organs. Soft tissue sarcomas can develop from soft tissues like fat, muscle, nerves, fibrous tissues, blood vessels, or deep skin tissues. This present study is a clinicopathological study of 155 cases of soft tissue tumours recorded over a period of 2 years. Among the 155 cases, 4,045 surgical biopsy materials received for the diagnosis, where 11.2% accounted soft tumours. The benign tumours accounted for 89.7% and malignant constituted 10.3%. Both benign and malignant soft tissue tumours showed sight preponderance to female population. Benign soft tissue tumours showed predilection for head and neck region whereas malignant showed for lower extremities. Benign soft tissue tumours presented as painless mass while malignant soft tissue tumour presented with longer duration. The commonest benign tumours are lipoma, vascular, neural, fibrous, smooth muscle and fibrous histiocytic; the commonest malignant tumours are liposarcoma and malignant peripheral nerve sheath tumour, angiosarcomas, fibrosarcomas, synovial sarcoma and malignant fibrous histiocytoma. Special stains are helpful in addition to the routine haematoxylin and eosin for the proper diagnosis of soft tissue sarcomas and guide further course of management.

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