Fokunang Charles Ntungwen
The discovery of antibiotics has contributed considerably to up the life of the world population. Nowadays, the emergence of multi resistant strains of bacterium worldwide may be a major concern because it dramatically reduces the selection of effective antibiotics for interference and treatment of a awfully common infection in each hospitals and our native communities. The aim of this study was to judge the in vitro interaction of Polymox and Annickia chlorantha against some Multi resistant bacterium strains. The interaction between Polymox and Annickia chlorantha was studied victimization the gameboard technique. incomplete restrictive Concentration (FIC) indices showed that Amoxicillin/Annickia chlorantha combination was synergistic against the clinical stock of salmonella at concentrations of 5: fifteen and twenty five mg/mL. The extracts of the stem barks of Annickia chlorantha decreased the minimum restrictive concentration (MIC) of Polymox against salmonella by 2: four and sixty six folds severally. At a similar concentrations the mix showed no distinction against the reference stocks of staph aureus and a dose dependent antagonism against clinical stock of Escherichia coli. The results of this study discovered that the concomitant use of Annickia chlorantha and Polymox could raise and restore the medicament impact of Polymox against resistant strains of salmonella. this suggests that the intake of Annickia chlorantha in ancient medicines could have an effect on the effectiveness of a co-administered Polymox, that makes this plant a decent, environmentally friendly associate degreed promising candidate for the event of an improved ancient medication. Study sites and plant identification A.