European Journal of Experimental Biology Open Access

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Abstract

Effect of eight weeks of moderate aerobic activity, the changes in obestatin and insulin plasma in male obese sprague dawley rats

Maryam Mehboodi, Eskandar Rahimi and Sirous Choobineh

Today, a sedentary lifestyle, the risk of metabolic syndrome and two internal secretion, i.e. obesity and diabetes increases. The aim of this study was to compare the effects of two types of exercise, the changes in plasma obestatin and insulin in obese male rats of the sprague dawley. Then, randomly, 50 rats aged three months, were selected and divided into two groups after the exercise and control groups, the 8-week training program conducted. In controlled laboratory conditions, 24 hours after the last exercise, of all groups, blood samples were taken. For the measurement of plasma obestatin and insulin, blood samples to the lab moved. The findings showed that, with practice, obestatin and insulin levels decreased significantly (P=0.05), and between obestatin and insulin reduction,moderate-intensity exercise group, a significant correlation (r=0.048), see are. Results showed that aerobic exercise reduces obestatin and insulin levels in plasma are. May exercise, by improving energy levels in obesity and diabetes might be effective.