Journal of Intensive and Critical Care Open Access

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Continuous Renal Replacement Therapy for Acute Kidney Injuries after Cardiac Surgery-Insights from a Single Cardiovascular Institute

Genta Chikazawa*, Arudo Hiraoka, Genta Chikazawa, Tomoya Ohshita, Satoko Ishii, Toshinori Totsugawa and Hidenori Yoshitaka

Background: Acute kidney injury (AKI) is not an unusual clinical complication after cardiovascular surgery. The aim of this study was to investigate the clinical significance of continuous renal replacement therapy (CRRT) in managing postoperative AKI.

Material and methods: 243 patients who received cardiovascular surgery complicated with postoperative AKI in cardiovascular intensive care (CVICU) were enrolled. Patients were divided into two groups: those requiring CRRT (Group A, n=64) and those not administered CRRT (Group B, n=179).

Results: Preoperative backgrounds showed there were more surgically at-risk patients complicated with a poorer renal profile in Group A. Procedure-related data identified cardiopulmonary bypass (CPB) and aortic cross clamp (ACC) times were significantly longer in Group A. Also, in-hospital mortality and hemodialysis transition rates were significantly higher in Group A. Preoperative renal profile and male gender was identified as risk factors for hemodialysis transition post cardiovascular surgery.

Conclusion: CRRT is expected to play a vital role in managing AKI post cardiovascular surgery. Further investigation is warranted to clarify the efficacy of CRRT for the improvement of long-term outcomes of patients complicated with postoperative AKI.

Published Date: 2022-02-23; Received Date: 2022-01-26