European Journal of Experimental Biology Open Access

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Comparative Levels of ALT, AST, ALP and GGT in Liver associated Diseases

Mohd Azam Hyder, Marghoob Hasan and Abdelmarouf Hassan Mohieldein

Hepatic injury is associated with distortion of the metabolic function. Hepatic disease can be evaluated by biochemical analysis of the serum tests, includes levels of serum Alanine and Aspartate aminotransferases, alkaline phosphatase, and others. The present study was conducted to assay Liver associated enzymes on patients with Viral Hepatitis, Alcoholic liver diseases, and Liver cirrhosis and to find out the comparative levels of enzymes between the groups. In this study, total 60 male subjects (15 Healthy controls and 45 patients “Case group”) aged between 30 to 50 years was enrolled. Each case group consisted of 15 male patients suffering with Viral Hepatitis, Alcoholic Liver disease (more than 10 years) and liver cirrhosis respectively. Serum levels of Alanine and Aspartate aminotransferases, alkaline phosphatase and Gamma glutamyle transferase were analyzed using standard methods. Data analyzed using SPSS Version 17.0 Several folds of variation in the analyzed enzymes were found between healthy control and case groups. Comparative elevation of Liver associated enzymes was observed to indicate the degree of Hepatic Damage in Viral Hepatitis, Alcoholic liver diseases and cirrhosis