Annals of Clinical Nephrology Open Access

Abstract

CMIP in Autoimmunity and Cancers: Friend or Foe

Dil Sahali* and Mario Ollero

Malignant tumors result from a succession of alterations in genomic and epigenomic patterns, including gene mutations, changes in DNA methylation, post-translational histone modifications, or chromatin structure. Malignancies share several pathogenic features with autoimmune diseases, such as immune dysregulation, genetic and environmental factors.