American Journal of Advanced Drug Delivery Open Access

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Abstract

Bermuda Grass (Cynodon dactylon) Extracts and its Effect on Lipid Profile Assay of Streptozotocin-induced Wistar Albino rats

Edeh I.E., Uwakwe A.A. and Chuku L.C.

Aqueous and Ethanolic extracts of Cynodon dactylon and their effects on Lipidprofile assay of streptozotocin–induced diabetic Wistar albino rats were investigated. Diabetes mellitus was induced by treatment with streptozotocin. Aqueous and ethanolic extracts of Cynodon dactylon at varying concentrations (300mg, 500mg and 700mg/kg body weight) were administered to the diabetic rats. Aqueous and ethanolic extract of herbal preparation of the Bermuda grass (Cynodon dactylon) showed a significantly decrease (p<0.05) in the lipid profile (cholesterol, triglyceride, and HDL), but the decrease was not progressive, hence they occurred a varying interval. The extract(s) of the grass (i.e. herbal preparation) has no significant (p>0.05) effect on LDL within the duration of treatment at different concentrations. The results of this study strongly suggest that Cynodon dactylon possess hypolipidemic properties with the exception of LDL.