Advances in Applied Science Research Open Access

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Antifungal activity of some plant extracts against Clinical Pathogens

Abhishek Mathur, Ravinder Singh, Sajad Yousuf, Aprajita Bhardwaj, Satish K. Verma, Pradeep Babu, Vinay Gupta, GBKS Prasad and V.K. Dua

The antifungal activity and minimum inhibitory concentration (MIC) of various plant extracts in different solvents such as hydro-alcohol (50 % v/v) and hexane of plants traditionally used as medicines as Valeriana jatamansi (Sugandhbala), Coleus barbatus (Pathar choor), Berberis aristata (Kingore), Asparagus racemosus (Satrawal), Andrographis paniculata (Kalmegha), Achyranthes aspera (Latjiri), Tinospora cordifolia (Giloei), Plantago depressa (Isabgol) were evaluated against Aspergillus niger and Candida albicans. Hydro-alcoholic extracts of all the plants were found to have maximum antifungal activity in comparison to hexane extracts. Hydroalcoholic extracts of Andrographis paniculata and Achyranthes aspera showed maximum potency against Aspergillus niger and Candida albicans at highest MIC value of 0.5 and 0.3 mg/ml respectively. Hexane extracts of Andrographis paniculata showed highest MIC value of 0.7 mg/ml against Aspergillus niger.

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