European Journal of Experimental Biology Open Access

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Abstract

A Study on the drug resistance of probiotic strains isolated from commercial probotic products available in the local market of Agra

Jagriti Sharma and Ankur Goyal

Probiotics are well known to put positive health effects upon the humans and animals are now being used as medicines to combat the diseases due to their ability to inhibit the pathogenic microorganisms. This study evaluates their susceptibility towards the different drugs which could be an important parameter in the abovementioned regard. For this the probiotic strains were isolated from the commercial probotic products and their drug susceptibility was assessed by using Kirby Bauer disc diffusion method against the readymade antibiotic discs of Amikacin, Azithromycin, Levofloxacin, Ceftazidime, Chloramphenicol, Aztreonam, Amoxycillin/Clavulanate, Ciprofloxacin, Piperacillin/tozobactum, Nitrofurantoin and meropenem. Almost 80% of the probotic strains were found to show resistance for the drugs Ceftazidime Amoxycillin/Clavulanate and Aztreonam but highly sensitive to Ciprofloxacin, Meropenam, Levafloxacin, Chloramphenical, Amikacin and piperacillin/tozobactum while showed intermediate sensitivity for the drugs Nitrofurantoin and Azithromycin. Rest of the 20% strains showed intermediate to high sensitivity against the abovementioned drugs without any resistance case.