Advances in Applied Science Research Open Access

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Study on the changes in the levels of protein metabolism in ?Ž?» cyhalothrininduced hepatotoxicity in fresh water Tilapia (Oreochromis Mossambicus).

Rekha Parthasarathy and John Joseph

An attempt has been made to determine the deleterious effects of λ cyhalothrin-induced in fresh water tilapia (O.mossambicus) with respect to changes in the level of protein in the liver. Significant (p<0.05) elevation in the level of lipid peroxidation was observed in Group IV [pesticide+ acetone 1.1μg/l] fishes as compared to controls. Significant (p<0.05) decline was also observed in protein content in Group IV [pesticide+ acetone 1.1μg/l] fishes as compared to controls. The result of the present study indicated that λ cyhalothrin elevates lipid peroxidation [LPO], consequently oxidative stress also induces changes in free radical production. As a result when the free radical production overwhelms the endogenous antioxidant levels, they cause considerable cell damage and death. Depletion of protein fraction in liver tissues may have been due to their degradation and possible utilization for metabolic purposes.

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