Journal of Drug Abuse Open Access

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Abstract

Nano Vplant-Development of lipid nanovesicles loaded with plant Extract

Pavaloiu Ramona Daniela

The aim of this study was to develop new lipid nanovesicles (transfersomes) loaded with various plant extracts (Sambucus ebulus L., Echinacea purpurea L., Lycium barbarum L., Armoracia rusticana L.) with applications in biomedical or cosmetic field. The plant extracts were loaded in lipid nanovesicles to improve their biodisponibility and to achieve an enhanced pharmacological effect. All selected plant extracts are used in traditional medicine for their anti-inflammatory, antioxidant,  antimicrobial, antiarthritic properties. Transfersomes loaded with Sambucus ebulus. The obtained nanovesicles showed good entrapment efficiency (>70%), nanometric sizes (<200 nm) and narrow polydispersity index